The Genetic Architectures of Functional and Structural Connectivity Properties within Cerebral Resting-State Networks.
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ABSTRACT:
SUBMITTER: Tissink E
PROVIDER: S-EPMC10089056 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
Publications
The Genetic Architectures of Functional and Structural Connectivity Properties within Cerebral Resting-State Networks.
Tissink Elleke E Werme Josefin J de Lange Siemon C SC Savage Jeanne E JE Wei Yongbin Y de Leeuw Christiaan A CA Nagel Mats M Posthuma Danielle D van den Heuvel Martijn P MP
eNeuro 20230410 4
Functional connectivity within resting-state networks (RSN-FC) is vital for cognitive functioning. RSN-FC is heritable and partially translates to the anatomic architecture of white matter, but the genetic component of structural connections of RSNs (RSN-SC) and their potential genetic overlap with RSN-FC remain unknown. Here, we perform genome-wide association studies (<i>N</i> <sub>discovery</sub> = 24,336; <i>N</i> <sub>replication</sub> = 3412) and annotation on RSN-SC and RSN-FC. We identif ...[more]
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