Ontology highlight
ABSTRACT:
SUBMITTER: Razzokov J
PROVIDER: S-EPMC10094641 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Razzokov Jamoliddin J Fazliev Sunnatullo S Makhkamov Mukhriddin M Marimuthu Parthiban P Baev Artyom A Kurganov Erkin E
International journal of molecular sciences 20230328 7
The self-association of amylogenic proteins to the fibril form is considered a pivotal factor in the pathogenesis of neurodegenerative diseases, including Parkinson's disease (PD). PD causes unintended or uncontrollable movements in its common symptoms. α-synuclein is the major cause of PD development and thus has been the main target of numerous studies to suppress and sequester its expression or effectively degrade it. Nonetheless, to date, there are no efficient and proven ways to prevent pat ...[more]