Ontology highlight
ABSTRACT:
SUBMITTER: Martins I
PROVIDER: S-EPMC10094762 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Martins Isaura I Neves-Silva Dalila D Ascensão-Ferreira Mariana M Dias Ana Filipa AF Ribeiro Daniel D Isidro Ana Filipa AF Quitéria Raquel R Paramos-de-Carvalho Diogo D Barbosa-Morais Nuno L NL Saúde Leonor L
International journal of molecular sciences 20230329 7
Traumatic spinal cord injury (SCI) initiates a cascade of cellular events, culminating in irreversible tissue loss and neuroinflammation. After the trauma, the blood vessels are destroyed. The blood-spinal cord barrier (BSCB), a physical barrier between the blood and spinal cord parenchyma, is disrupted, facilitating the infiltration of immune cells, and contributing to a toxic spinal microenvironment, affecting axonal regeneration. Understanding how the vascular constituents of the BSCB respond ...[more]