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Age at first childbirth and the risk of hypertriglyceridemia among Korean women.


ABSTRACT:

Objectives

We aimed to investigate the association of age at first childbirth with the risk of hypertriglyceridemia among Korean women.

Methods

This study used data from the Korean genome and epidemiology study of the cardiovascular disease association study. A total of 16,747 women were included in the cross-sectional analysis, and 6,250 women were included in the longitudinal analysis. The participants were divided based on their age at first childbirth (<20 years, 20-24 years, 25-29 years, and ≥30 years). Hypertriglyceridemia was defined as triglyceride levels of >150 mg/dL.

Results

The multivariable-adjusted odds ratio (95% CI) for prevalent hypertriglyceridemia was 1.19 (1.01-1.40) in women with first childbirth <20 years, compared to those with first childbirth at 25-29 years, after adjusted for age, study site, body mass index, blood pressure, diabetes, alcohol consumption, carbohydrate intake, income, marital status, education, parity, usage of oral contraceptives, and hormone replacement status. During a median follow-up of 5.2 years, 1,770 women developed hypertriglyceridemia. Compared with women giving birth to their first child between 25 and 29 years of age, those giving birth to their first child before 20 years of age had a higher risk for incident hypertriglyceridemia in later life (Adjusted hazard ratio: 1.25, 95% CI: 0.99-1.57).

Conclusion

Giving birth to the first child before the age of 20 years was significantly associated with an increased risk of hypertriglyceridemia among Korean women.

SUBMITTER: Choi HR 

PROVIDER: S-EPMC10106550 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature

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Publications

Age at first childbirth and the risk of hypertriglyceridemia among Korean women.

Choi Hye Rin HR   Kim Hyeon Chang HC  

Epidemiology and health 20221229


<h4>Objectives</h4>We aimed to investigate the association of age at first childbirth with the risk of hypertriglyceridemia among Korean women.<h4>Methods</h4>This study used data from the Korean Genome and Epidemiology Study-Cardiovascular Disease Association Study. In total, 16,747 women were included in the cross-sectional analysis, and 6,250 women were included in the longitudinal analysis. The participants were divided based on their age at first childbirth (<20, 20-24, 25-29, and ≥30 years  ...[more]

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