Ontology highlight
ABSTRACT:
SUBMITTER: Lin A
PROVIDER: S-EPMC10108709 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
Lin Andy A Short Temana T Noble William Stafford WS Keich Uri U
Journal of proteome research 20220927 10
The analysis of shotgun proteomics data often involves generating lists of inferred peptide-spectrum matches (PSMs) and/or of peptides. The canonical approach for generating these discovery lists is by controlling the false discovery rate (FDR), most commonly through target-decoy competition (TDC). At the PSM level, TDC is implemented by competing each spectrum's best-scoring target (real) peptide match with its best match against a decoy database. This PSM-level procedure can be adapted to the ...[more]