Ontology highlight
ABSTRACT:
SUBMITTER: Kriebel CN
PROVIDER: S-EPMC10111219 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Kriebel Clara Nassrin CN Asido Marvin M Kaur Jagdeep J Orth Jennifer J Braun Philipp P Becker-Baldus Johanna J Wachtveitl Josef J Glaubitz Clemens C
Biophysical journal 20221217 6
Krokinobacter eikastus rhodopsin 2 (KR2) is a light-driven pentameric sodium pump. Its ability to translocate cations other than protons and to create an electrochemical potential makes it an attractive optogenetic tool. Tailoring its ion-pumping characteristics by mutations is therefore of great interest. In addition, understanding the functional and structural consequences of certain mutations helps to derive a functional mechanism of ion selectivity and transfer of KR2. Based on solid-state N ...[more]