Ontology highlight
ABSTRACT:
SUBMITTER: Okenu DM
PROVIDER: S-EPMC101506 | biostudies-literature | 2000 Oct
REPOSITORIES: biostudies-literature
Okenu D M DM Riley E M EM Bickle Q D QD Agomo P U PU Barbosa A A Daugherty J R JR Lanar D E DE Conway D J DJ
Infection and immunity 20001001 10
Invasion of human erythrocytes by Plasmodium falciparum merozoites is a multistep process. For many strains of the parasite, part of this process requires that the erythrocyte binding antigen 175 (EBA-175) of the merozoite binds to sialic acid residues of glycophorin A on the erythrocyte surface, a receptor-ligand interaction which represents a potential target for inhibition by antibodies. This study characterizes the reactivity of naturally acquired human antibodies with four recombinant prote ...[more]