Ontology highlight
ABSTRACT:
SUBMITTER: Lee HN
PROVIDER: S-EPMC10156165 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
Lee Han Nim HN Chacko Jenu Varghese JV Gonzalez Solís Ariadna A Chen Kuo-En KE Barros Jessica A S JAS Signorelli Santiago S Millar A Harvey AH Vierstra Richard David RD Eliceiri Kevin W KW Otegui Marisa S MS
eLife 20230418
The ubiquitin-binding NBR1 autophagy receptor plays a prominent role in recognizing ubiquitylated protein aggregates for vacuolar degradation by macroautophagy. Here, we show that upon exposing <i>Arabidopsis</i> plants to intense light, NBR1 associates with photodamaged chloroplasts independently of ATG7, a core component of the canonical autophagy machinery. NBR1 coats both the surface and interior of chloroplasts, which is then followed by direct engulfment of the organelles into the central ...[more]