Ontology highlight
ABSTRACT:
SUBMITTER: Matusova Z
PROVIDER: S-EPMC10157076 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Matusova Zuzana Z Hol Elly M EM Pekny Milos M Kubista Mikael M Valihrach Lukas L
Frontiers in cellular neuroscience 20230420
Reactive astrogliosis is a reaction of astrocytes to disturbed homeostasis in the central nervous system (CNS), accompanied by changes in astrocyte numbers, morphology, and function. Reactive astrocytes are important in the onset and progression of many neuropathologies, such as neurotrauma, stroke, and neurodegenerative diseases. Single-cell transcriptomics has revealed remarkable heterogeneity of reactive astrocytes, indicating their multifaceted functions in a whole spectrum of neuropathologi ...[more]