Ontology highlight
ABSTRACT:
SUBMITTER: Wang EJ
PROVIDER: S-EPMC10157272 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Wang Er-Jin EJ Wu Ming-Yue MY Ren Zheng-Yu ZY Zheng Ying Y Ye Richard D RD Tan Chris Soon Heng CSH Wang Yitao Y Lu Jia-Hong JH
Burns & trauma 20230504
Inflammatory bowel disease (IBD) is a chronic, non-specific, recurrent inflammatory disease, majorly affecting the gastrointestinal tract. Due to its unclear pathogenesis, the current therapeutic strategy for IBD is focused on symptoms alleviation. Autophagy is a lysosome-mediated catabolic process for maintaining cellular homeostasis. Genome-wide association studies and subsequent functional studies have highlighted the critical role of autophagy in IBD via a number of mechanisms, including mod ...[more]