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Nucleotide sequence of the chromosomal ampC gene of Enterobacter aerogenes.


ABSTRACT: The AmpC beta-lactamase gene and a small portion of the regulatory ampR sequence of Enterobacter aerogenes 97B were cloned and sequenced. The beta-lactamase had an isoelectric point of 8 and conferred cephalosporin and cephamycin resistance on the host. The sequence of the cloned gene is most closely related to those of the ampC genes of E. cloacae and C. freundii.

SUBMITTER: Preston KE 

PROVIDER: S-EPMC101621 | biostudies-literature | 2000 Nov

REPOSITORIES: biostudies-literature

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Nucleotide sequence of the chromosomal ampC gene of Enterobacter aerogenes.

Preston K E KE   Radomski C C CC   Venezia R A RA  

Antimicrobial agents and chemotherapy 20001101 11


The AmpC beta-lactamase gene and a small portion of the regulatory ampR sequence of Enterobacter aerogenes 97B were cloned and sequenced. The beta-lactamase had an isoelectric point of 8 and conferred cephalosporin and cephamycin resistance on the host. The sequence of the cloned gene is most closely related to those of the ampC genes of E. cloacae and C. freundii. ...[more]

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