Ontology highlight
ABSTRACT:
SUBMITTER: Thomas A
PROVIDER: S-EPMC10168218 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
bioRxiv : the preprint server for biology 20230424
Action selection occurs through competition between potential choice options. Neural correlates of choice competition are observed across frontal cortex and downstream superior colliculus (SC) during decision-making, yet how these regions interact to mediate choice competition remains unresolved. Here we report that cell types within SC can bidirectionally modulate choice competition and drive choice activity in frontal cortex. In the mouse, topographically matched regions of frontal cortex and ...[more]