Ontology highlight
ABSTRACT:
SUBMITTER: Daniel B
PROVIDER: S-EPMC10168641 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Daniel Bastian B Hashem Chiam C Leithold Marlene M Sagmeister Theo T Tripp Adrian A Stolterfoht-Stock Holly H Messenlehner Julia J Keegan Ronan R Winkler Christoph K CK Ling Jonathan Guyang JG Younes Sabry H H SHH Oberdorfer Gustav G Abu Bakar Farah Diba FD Gruber Karl K Pavkov-Keller Tea T Winkler Margit M
ACS catalysis 20221206 24
The synthesis of aldehydes from carboxylic acids has long been a challenge in chemistry. In contrast to the harsh chemically driven reduction, enzymes such as carboxylic acid reductases (CARs) are considered appealing biocatalysts for aldehyde production. Although structures of single- and didomains of microbial CARs have been reported, to date no full-length protein structure has been elucidated. In this study, we aimed to obtain structural and functional information regarding the reductase (R) ...[more]