Ontology highlight
ABSTRACT:
SUBMITTER: Upadhyaya M
PROVIDER: S-EPMC1017052 | biostudies-literature | 1991 Oct
REPOSITORIES: biostudies-literature
Upadhyaya M M Lunt P W PW Sarfarazi M M Broadhead W W Daniels J J Owen M M Harper P S PS
Journal of medical genetics 19911001 10
Close linkage of a hypervariable DNA probe on chromosome 4q (pH30, locus D4S139) has been found with the locus for facioscapulohumeral disease. Three recombinants were identified in a total of 140 meioses, giving a maximum lod score of 36.77 at a recombination fraction of 0.02. All but two of the families studied proved informative with this probe; all informative families showed evidence of linkage (except one family with a single scorable meiosis), making genetic heterogeneity unlikely from ou ...[more]