Ontology highlight
ABSTRACT:
SUBMITTER: Kamdar RD
PROVIDER: S-EPMC10178396 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
Kamdar Rahul D RD Harrington Brittney S BS Attar Emma E Korrapati Soumya S Shetty Jyoti J Zhao Yongmei Y Tran Bao B Wong Nathan N House Carrie D CD Annunziata Christina M CM
International journal of molecular sciences 20230425 9
Epithelial ovarian cancer (EOC) remains the fifth leading cause of cancer-related death in women worldwide, partly due to the survival of chemoresistant, stem-like tumor-initiating cells (TICs) that promote disease relapse. We previously described a role for the NF-κB pathway in promoting TIC chemoresistance and survival through NF-κB transcription factors (TFs) RelA and RelB, which regulate genes important for the inflammatory response and those associated with cancer, including microRNAs (miRN ...[more]