Unknown

Dataset Information

0

Single Center, Propensity Score Matching Analysis of Different Reconstruction Techniques following Pancreatoduodenectomy.


ABSTRACT:

Background

Pancreatoduodenectomy is still hampered by significant morbidity. So far, there is no universally accepted technique aimed at minimizing postoperative complications. Herein, we compare three different reconstruction techniques.

Methods

This is a retrospective study of a prospectively maintained database including 283 patients operated between January 2010 and December 2020. Three reconstruction techniques were compared: (1) the Neuhaus-style telescope pancreatojejunostomy, (2) the pancreatogastrostomy, and (3) the modified Blumgart-style, duct-to-mucosa pancreatojejunostomy. The primary endpoint consisted in determining the rates of clinically relevant postoperative pancreatic fistulas (CR-POPF); the secondary endpoints included 90 days morbidity and mortality rates. A propensity score matching analysis was used.

Results

Rates of CR-POPF did not differ significantly between the groups (Neuhaus-style pancreatojejunostomy 16%, pancreatogastrostomy 17%, modified Blumgart-style pancreatojejunostomy 15%), neither in the unmatched nor in the matched analysis (p = 0.993 and p = 0.901, respectively). Similarly, no significant differences could be observed with regard to major morbidity (unmatched p = 0.596, matched p = 0.188) and mortality rates (unmatched p = 0.371, matched p = 0.209) within the first 90 days following surgery. Propensity-score matching analyses revealed, however, a higher occurrence of post-pancreatectomy hemorrhage after pancreatogastrostomy (p = 0.015).

Conclusion

Similar CR-POPF rates suggest no crucial role of the applied reconstruction technique. Increased incidence of intraluminal post-pancreatectomy hemorrhages following pancreatogastrostomy demands awareness for meticulous hemostasis.

SUBMITTER: Bellotti R 

PROVIDER: S-EPMC10179219 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature

altmetric image

Publications

Single Center, Propensity Score Matching Analysis of Different Reconstruction Techniques following Pancreatoduodenectomy.

Bellotti Ruben R   Cardini Benno B   Strolz Carola J CJ   Stättner Stefan S   Oberhuber Rupert R   Braunwarth Eva E   Resch Thomas T   Scheidl Stefan S   Margreiter Christian C   Schneeberger Stefan S   Öfner Dietmar D   Maglione Manuel M  

Journal of clinical medicine 20230506 9


<h4>Background</h4>Pancreatoduodenectomy is still hampered by significant morbidity. So far, there is no universally accepted technique aimed at minimizing postoperative complications. Herein, we compare three different reconstruction techniques.<h4>Methods</h4>This is a retrospective study of a prospectively maintained database including 283 patients operated between January 2010 and December 2020. Three reconstruction techniques were compared: (1) the Neuhaus-style telescope pancreatojejunosto  ...[more]

Similar Datasets

| S-EPMC6993337 | biostudies-literature
| S-EPMC11191888 | biostudies-literature
| S-EPMC8743702 | biostudies-literature
| S-EPMC10898866 | biostudies-literature
| S-EPMC7262885 | biostudies-literature
| S-EPMC9994691 | biostudies-literature
| S-EPMC6781555 | biostudies-literature
| S-EPMC9343849 | biostudies-literature
| S-EPMC3407414 | biostudies-literature
| S-EPMC8436703 | biostudies-literature