Ontology highlight
ABSTRACT:
SUBMITTER: Chen Y
PROVIDER: S-EPMC10192429 | biostudies-literature | 2023 May
REPOSITORIES: biostudies-literature
Chen Yuli Y Li Haojia H Janowczyk Andrew A Toro Paula P Corredor Germán G Whitney Jon J Lu Cheng C Koyuncu Can F CF Mokhtari Mojgan M Buzzy Christina C Ganesan Shridar S Feldman Michael D MD Fu Pingfu P Corbin Haley H Harbhajanka Aparna A Gilmore Hannah H Goldstein Lori J LJ Davidson Nancy E NE Desai Sangeeta S Parmar Vani V Madabhushi Anant A
NPJ breast cancer 20230517 1
Prognostic markers currently utilized in clinical practice for estrogen receptor-positive (ER+) and lymph node-negative (LN-) invasive breast cancer (IBC) patients include the Nottingham grading system and Oncotype Dx (ODx). However, these biomarkers are not always optimal and remain subject to inter-/intra-observer variability and high cost. In this study, we evaluated the association between computationally derived image features from H&E images and disease-free survival (DFS) in ER+ and LN- I ...[more]