Ontology highlight
ABSTRACT:
SUBMITTER: Hu JJ
PROVIDER: S-EPMC10196962 | biostudies-literature | 2023 Jun
REPOSITORIES: biostudies-literature
Hu Jing-Jing JJ Yu Xue-Zhao XZ Zhang Shu-Qin SQ Zhang Yu-Xuan YX Chen Xiao-Lin XL Long Zhu-Jun ZJ Hu Hua-Zhong HZ Xie Deng-Hui DH Zhang Wen-Hua WH Chen Jin-Xiang JX Zhang Qun Q
iScience 20230429 6
The strategies for eliminating excess reactive oxygen species (ROS) or suppressing inflammatory responses on the wound bed have proven effective for diabetic wound healing. In this work, a zinc-based nanoscale metal-organic framework (NMOF) functions as a carrier to deliver natural product berberine (BR) to form BR@Zn-BTB nanoparticles, which was, in turn, further encapsulated by hydrogel with ROS scavenging ability to yield a composite system of BR@Zn-BTB/Gel (denoted as BZ-Gel). The results sh ...[more]