Dataset Information

Long-Term Outcomes of the Excluded Rectum in Crohn's Disease: A Multicenter International Study.

ABSTRACT:

Background

Many patients with Crohn's disease (CD) require fecal diversion. To understand the long-term outcomes, we performed a multicenter review of the experience with retained excluded rectums.

Methods

We reviewed the medical records of all CD patients between 1990 and 2014 who had undergone diversionary surgery with retention of the excluded rectum for at least 6 months and who had at least 2 years of postoperative follow-up.

Results

From all the CD patients in the institutions' databases, there were 197 who met all our inclusion criteria. A total of 92 (46.7%) of 197 patients ultimately underwent subsequent proctectomy, while 105 (53.3%) still had retained rectums at time of last follow-up. Among these 105 patients with retained rectums, 50 (47.6%) underwent reanastomosis, while the other 55 (52.4%) retained excluded rectums. Of these 55 patients whose rectums remained excluded, 20 (36.4%) were symptom-free, but the other 35 (63.6%) were symptomatic. Among the 50 patients who had been reconnected, 28 (56%) were symptom-free, while 22(44%) were symptomatic. From our entire cohort of 197 cases, 149 (75.6%) either ultimately lost their rectums or remained symptomatic with retained rectums, while only 28 (14.2%) of 197, and only 4 (5.9%) of 66 with initial perianal disease, were able to achieve reanastomosis without further problems. Four patients developed anorectal dysplasia or cancer.

Conclusions

In this multicenter cohort of patients with CD who had fecal diversion, fewer than 15%, and only 6% with perianal disease, achieved reanastomosis without experiencing disease persistence.

SUBMITTER: Kassim G

PROVIDER: S-EPMC10210615 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature

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Publications

Long-Term Outcomes of the Excluded Rectum in Crohn's Disease: A Multicenter International Study.

Kassim Gassan G Yzet Clara C Nair Nilendra N Debebe Anketse A Rendon Alexa A Colombel Jean-Frédéric JF Traboulsi Cindy C Rubin David T DT Maroli Annalisa A Coppola Elisabetta E Carvello Michele M MM Ben David Nadat N De Lucia Francesca F Sacchi Matteo M Danese Silvio S Spinelli Antonino A Hirdes Meike M C MMC Ten Hove Joren J Oldenburg Bas B Cholapranee Aurada A Riter Maxine M Lukin Dana D Scherl Ellen E Eren Esen E Sultan Keith S KS Axelrad Jordan J Sachar David B DB

Inflammatory bowel diseases 20230301 3

<h4>Background</h4>Many patients with Crohn's disease (CD) require fecal diversion. To understand the long-term outcomes, we performed a multicenter review of the experience with retained excluded rectums.<h4>Methods</h4>We reviewed the medical records of all CD patients between 1990 and 2014 who had undergone diversionary surgery with retention of the excluded rectum for at least 6 months and who had at least 2 years of postoperative follow-up.<h4>Results</h4>From all the CD patients in the ins ...[more]

PMID: 35522225

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Dataset Information

Long-Term Outcomes of the Excluded Rectum in Crohn's Disease: A Multicenter International Study.

Background

Methods

Results

Conclusions

Publications

Long-Term Outcomes of the Excluded Rectum in Crohn's Disease: A Multicenter International Study.

Similar Datasets

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