Ontology highlight
ABSTRACT:
SUBMITTER: Clavel P
PROVIDER: S-EPMC10214834 | biostudies-literature | 2023 May
REPOSITORIES: biostudies-literature
Clavel Pierre P Louis Lexane L Sarkissian Clio Der C Thèves Catherine C Gillet Claudia C Chauvey Lorelei L Tressières Gaétan G Schiavinato Stéphanie S Calvière-Tonasso Laure L Telmon Norbert N Clavel Benoît B Jonvel Richard R Tzortzis Stéfan S Bouniol Laetitia L Fémolant Jean-Marc JM Klunk Jennifer J Poinar Hendrik H Signoli Michel M Costedoat Caroline C Spyrou Maria A MA Seguin-Orlando Andaine A Orlando Ludovic L
iScience 20230502 5
Ancient DNA preserved in the dental pulp offers the opportunity to characterize the genome of some of the deadliest pathogens in human history. However, while DNA capture technologies help, focus sequencing efforts, and therefore, reduce experimental costs, the recovery of ancient pathogen DNA remains challenging. Here, we tracked the kinetics of ancient <i>Yersinia pestis</i> DNA release in solution during a pre-digestion of the dental pulp. We found that most of the ancient <i>Y. pestis</i> DN ...[more]