Ontology highlight
ABSTRACT:
SUBMITTER: Chen H
PROVIDER: S-EPMC10216005 | biostudies-literature | 2023 May
REPOSITORIES: biostudies-literature
Chen He H Liu Hao H Ji Yanran Y Sha Zekun Z An Li L Li Meng M Zhang Di D Wu Xujin X Hua Xiude X
Biosensors 20230513 5
Pyridaben, a broad-spectrum pyridazinone acaricide that is widely used in agricultural production, can induce neurotoxicity and reproductive abnormalities, and is highly toxic to aquatic organisms. In this study, a pyridaben hapten was synthesized and used to prepare monoclonal antibodies (mAbs), among which 6E3G8D7 showed the highest sensitivity in indirect competitive enzyme-linked immunosorbent assay, with a 50% inhibitory concentration (IC<sub>50</sub>) of 3.49 ng mL<sup>-1</sup>. The mAb, 6 ...[more]