Ontology highlight
ABSTRACT:
SUBMITTER: Tomlin GC
PROVIDER: S-EPMC102262 | biostudies-literature | 2002 Apr
REPOSITORIES: biostudies-literature
Tomlin Gregory C GC Morrell Jennifer L JL Gould Kathleen L KL
Molecular biology of the cell 20020401 4
The Schizosaccharomyces pombe septation initiation network (SIN) signals the onset of cell division from the spindle pole body (SPB) and is regulated by the small GTPase Spg1p. The localization of SIN components including Spg1p to the SPB is required for cytokinesis and is dependent on Sid4p, a constitutive resident of SPBs. However, a direct interaction between Sid4p and other members of the SIN has not been detected. To understand how Sid4p is linked to other SIN components, we have begun to c ...[more]