Ontology highlight
ABSTRACT:
SUBMITTER: Peng F
PROVIDER: S-EPMC10242197 | biostudies-literature | 2023 Jun
REPOSITORIES: biostudies-literature
Peng Fang F Xu Qiushi Q Jing Xiaomeng X Chi Xinming X Zhang Zheming Z Meng Xiangpeng X Liu Xinyuan X Yan Jiao J Liu Xuefeng X Shao Shujuan S
FASEB bioAdvances 20230408 6
Lung cancer, with non-small cell lung cancer (NSCLC) being the main subtype, is the leading cause of cancer death worldwide, which is mainly due to the cancer metastasis. Glutathione peroxidase 2 (GPX2), an antioxidant enzyme, is involved in tumor progression and metastasis. Nevertheless, the role of GPX2 in NSCLC metastasis has not been clarified. In this study, we found that GPX2 expression was elevated in NSCLC tissues and high GPX2 expression was correlated with poor prognosis in patients wi ...[more]