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Nonequilibrium thermodynamics of the asymmetric Sherrington-Kirkpatrick model.

ABSTRACT: Most natural systems operate far from equilibrium, displaying time-asymmetric, irreversible dynamics characterized by a positive entropy production while exchanging energy and matter with the environment. Although stochastic thermodynamics underpins the irreversible dynamics of small systems, the nonequilibrium thermodynamics of larger, more complex systems remains unexplored. Here, we investigate the asymmetric Sherrington-Kirkpatrick model with synchronous and asynchronous updates as a prototypical example of large-scale nonequilibrium processes. Using a path integral method, we calculate a generating functional over trajectories, obtaining exact solutions of the order parameters, path entropy, and steady-state entropy production of infinitely large networks. Entropy production peaks at critical order-disorder phase transitions, but is significantly larger for quasi-deterministic disordered dynamics. Consequently, entropy production can increase under distinct scenarios, requiring multiple thermodynamic quantities to describe the system accurately. These results contribute to developing an exact analytical theory of the nonequilibrium thermodynamics of large-scale physical and biological systems and their phase transitions.

SUBMITTER: Aguilera M

PROVIDER: S-EPMC10290083 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature

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Nonequilibrium thermodynamics of the asymmetric Sherrington-Kirkpatrick model.

Aguilera Miguel M Igarashi Masanao M Shimazaki Hideaki H

Nature communications 20230623 1

Most natural systems operate far from equilibrium, displaying time-asymmetric, irreversible dynamics characterized by a positive entropy production while exchanging energy and matter with the environment. Although stochastic thermodynamics underpins the irreversible dynamics of small systems, the nonequilibrium thermodynamics of larger, more complex systems remains unexplored. Here, we investigate the asymmetric Sherrington-Kirkpatrick model with synchronous and asynchronous updates as a prototy ...[more]

PMID: 37353499

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Project description:ObjectivesTraining effectiveness indicates how good a program has met pre-set training objectives or organizational goals for the best benefit of healthcare professionals and service users in the community. The study aimed to evaluate training effectiveness following implementation of new training curriculum of emergency surgical airway procedures (Cricothyroidotomy) organized by the Queen Elizabeth Hospital.DesignThis training evaluation relied on observational descriptive study design. Timed task on Cricothyroidotomy procedures and standardized post-training questionnaire were applied to assess the first 3 levels of Kirkpatrick's model: (Level-1) Reaction by training satisfaction; (Level-2) Learning by acquisition of knowledge and skills assessment passing rate; (Level-3) Behavior by personal strengths.SettingThis program was operated in the Multi-Disciplinary Simulation and Skills Centre, a hospital-based high-fidelity simulation training center accredited by the Society for Simulation in Healthcare.ParticipantsThe study recruited 80 trauma service providers, including 35 general surgeons, 15 emergency physicians, 10 anesthesiologists or intensivists, 6 neurosurgeons, 4 orthopedic surgeons, and 10 emergency nurses from five trauma centers under the Hospital Authority. All underwent the Advanced Trauma Life Support training in advance.ResultsCompared with reference score from previous training sessions, the result of program using new training curriculum and simulator demonstrated significant training satisfaction of participants (Level-1), and high level of assertiveness, mental preparedness, self-efficacy, and internal locus of control and responsibility (p < .01, for all in Level-3). All participants (N = 80) completed entire Cricothyroidotomy procedure in 2 min without technical errors (Assessment passing rate = 100%) (Level-2).ConclusionsUnder Kirkpatrick model, simulation training in Cricothyroidotomy procedure using new curriculum and simulators has been proven to be useful for healthcare professionals involved in trauma service management. The result suggests that application of a state-of-the-art training tools to advanced surgical skills training could improve training satisfaction, knowledge and skills acquisition, and personal strengths transferable to clinical practice.Acgme competenciesPractice Based Learning and Improvement.

Dataset Information

Nonequilibrium thermodynamics of the asymmetric Sherrington-Kirkpatrick model.

Publications

Nonequilibrium thermodynamics of the asymmetric Sherrington-Kirkpatrick model.

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