Ontology highlight
ABSTRACT:
SUBMITTER: Sandomierski M
PROVIDER: S-EPMC10301584 | biostudies-literature | 2023 Jun
REPOSITORIES: biostudies-literature
Sandomierski Mariusz M Chojnacka Martyna M Długosz Maria M Pokora Monika M Zwolińska Joanna J Majchrzycki Łukasz Ł Voelkel Adam A
Materials (Basel, Switzerland) 20230613 12
Mercaptopurine is one of the drugs used in the treatment of acute lymphoblastic leukemia. A problem with mercaptopurine therapy is its low bioavailability. This problem can be solved by preparing the carrier that releases the drug in lower doses but over a longer period of time. In this work, polydopamine-modified mesoporous silica with adsorbed zinc ions was used as a drug carrier. SEM images confirm the synthesis of spherical carrier particles. The particle size is close to 200 nm, allowing fo ...[more]