Ontology highlight
ABSTRACT:
SUBMITTER: Bang JW
PROVIDER: S-EPMC10310759 | biostudies-literature | 2023 Jun
REPOSITORIES: biostudies-literature
Bang Ji Won JW Parra Carlos C Yu Kevin K Wollstein Gadi G Schuman Joel S JS Chan Kevin C KC
Communications biology 20230629 1
Glaucoma is an age-related neurodegenerative disease of the visual system, affecting both the eye and the brain. Yet its underlying metabolic mechanisms and neurobehavioral relevance remain largely unclear. Here, using proton magnetic resonance spectroscopy and functional magnetic resonance imaging, we investigated the GABAergic and glutamatergic systems in the visual cortex of glaucoma patients, as well as neural specificity, which is shaped by GABA and glutamate signals and underlies efficient ...[more]