Ontology highlight
ABSTRACT:
SUBMITTER: Metzger P
PROVIDER: S-EPMC10340358 | biostudies-literature | 2023 Jul
REPOSITORIES: biostudies-literature
Metzger Patrick P Hess Maria Elena ME Blaumeiser Andreas A Pauli Thomas T Schipperges Vincent V Mertes Ralf R Christoph Jan J Unberath Philipp P Reimer Niklas N Scheible Raphael R Illert Anna L AL Busch Hauke H Andrieux Geoffroy G Boerries Melanie M
Cancers 20230701 13
(1) Background: Next-generation sequencing (NGS) of patients with advanced tumors is becoming an established method in Molecular Tumor Boards. However, somatic variant detection, interpretation, and report generation, require in-depth knowledge of both bioinformatics and oncology. (2) Methods: MIRACUM-Pipe combines many individual tools into a seamless workflow for comprehensive analyses and annotation of NGS data including quality control, alignment, variant calling, copy number variation estim ...[more]