Ontology highlight
ABSTRACT:
SUBMITTER: Conti M
PROVIDER: S-EPMC10340604 | biostudies-literature | 2023 Jul
REPOSITORIES: biostudies-literature
Conti Matteo M Bolzacchini Elena E Luchena Giovanna G Bertu' Lorenza L Tagliabue Paola P Aglione Stefania S Ardizzoia Antonio A Arnoffi Jessica J Guida Francesco Maria FM Bertolini Alessandro A Pastorini Alessandro A Duro Maria M Bettega Donato D Roda' Giovambattista G Artale Salvatore S Squizzato Alessandro A Giordano Monica M
Cancers 20230702 13
Trifluridine/tipiracil (TAS-102) is an oral chemotherapy approved for the treatment of metastatic colorectal cancer. The efficacy and tolerability of TAS-102 were shown in phase II-III clinical trials and in several real-life studies. The elderly and other special subgroups are underrepresented in published literature. We conducted a retrospective multicenter study to assess the effectiveness and safety of TAS-102 in consecutive patients with pretreated mCRC. In particular, we estimated the effe ...[more]