Ontology highlight
ABSTRACT:
SUBMITTER: Reid SD
PROVIDER: S-EPMC103544 | biostudies-literature | 1999 Jan
REPOSITORIES: biostudies-literature
Reid S D SD Selander R K RK Whittam T S TS
Journal of bacteriology 19990101 1
To study the molecular evolution of flagellin, the protein subunit specifying flagellar (H) antigens, the fliC genes from 15 pathogenic strains of Escherichia coli were amplified by PCR and sequenced. Comparison of fliC sequences of H6 and H7 strains revealed that alleles have a mosaic structure indicating the occurrence of past horizontal transfer of DNA segments between strains. The close similarity of H7 sequences also indicates the exchange of an entire fliC H7 allele between distant clonal ...[more]