Ontology highlight
ABSTRACT:
SUBMITTER: Lee Y
PROVIDER: S-EPMC10355096 | biostudies-literature | 2023 Jul
REPOSITORIES: biostudies-literature
Chemical science 20230616 28
A novel mechanistic duality has been revealed from the indolyl 1,3-heteroatom transposition (IHT) of <i>N</i>-hydroxyindole derivatives. A series of in-depth mechanistic investigations suggests that two separate mechanisms are operating simultaneously. Moreover, the relative contribution of each mechanistic pathway, the energy barrier for each pathway, and the identity of the primary pathway were shown to be the functions of the electronic properties of the substrate system. Based on the mechani ...[more]