IL-1 in Abdominal Aortic Aneurysms.
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ABSTRACT:
SUBMITTER: Millar J
PROVIDER: S-EPMC10357974 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Publications
IL-1 in Abdominal Aortic Aneurysms.
Millar Jessica J Nasser Elias E Ailawadi Gorav G Salmon Morgan M
Journal of cellular immunology 20230101 2
Abdominal Aortic Aneurysms (AAA) remain a clinically devastating disease with no effective medical treatment therapy. AAAs are characterized by immune cell infiltration, smooth muscle cell apoptosis, and extracellular matrix degradation. Interleukin-1 (IL-1) has been shown to play role in AAA associated inflammation through immune cell recruitment and activation, endothelial dysfunction, production of reactive oxygen species (ROS), and regulation of transcription factors of additional inflammato ...[more]
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