Ontology highlight
ABSTRACT:
SUBMITTER: Price B
PROVIDER: S-EPMC103644 | biostudies-literature | 1999 Oct
REPOSITORIES: biostudies-literature
Price B B Adamidis T T Kong R R Champness W W
Journal of bacteriology 19991001 19
Streptomyces coelicolor produces four genetically and structurally distinct antibiotics in a growth-phase-dependent manner. S. coelicolor mutants globally deficient in antibiotic production (Abs(-) phenotype) have previously been isolated, and some of these were found to define the absB locus. In this study, we isolated absB-complementing DNA and show that it encodes the S. coelicolor homolog of RNase III (rnc). Several lines of evidence indicate that the absB mutant global defect in antibiotic ...[more]