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Hodological organization of spoken language production and singing in the human brain.

ABSTRACT: Theories expounding the neural relationship between speech and singing range from sharing neural circuitry, to relying on opposite hemispheres. Yet, hodological studies exploring their shared and distinct neural networks remain scarce. In this study, we combine a white matter connectometry approach together with comprehensive and naturalistic appraisal of verbal expression during spoken language production and singing in a sample of individuals with post-stroke aphasia. Our results reveal that both spoken language production and singing are mainly supported by the left hemisphere language network and projection pathways. However, while spoken language production mostly engaged dorsal and ventral streams of speech processing, singing was associated primarily with the left ventral stream. These findings provide evidence that speech and singing share core neuronal circuitry within the left hemisphere, while distinct ventral stream contributions explain frequently observed dissociations in aphasia. Moreover, the results suggest prerequisite biomarkers for successful singing-based therapeutic interventions.

SUBMITTER: Pitkaniemi A

PROVIDER: S-EPMC10371982 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature

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Hodological organization of spoken language production and singing in the human brain.

Pitkäniemi Anni A Särkämö Teppo T Siponkoski Sini-Tuuli ST Brownsett Sonia L E SLE Copland David A DA Sairanen Viljami V Sihvonen Aleksi J AJ

Communications biology 20230726 1

Theories expounding the neural relationship between speech and singing range from sharing neural circuitry, to relying on opposite hemispheres. Yet, hodological studies exploring their shared and distinct neural networks remain scarce. In this study, we combine a white matter connectometry approach together with comprehensive and naturalistic appraisal of verbal expression during spoken language production and singing in a sample of individuals with post-stroke aphasia. Our results reveal that b ...[more]

PMID: 37495670

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Dataset Information

Hodological organization of spoken language production and singing in the human brain.

Publications

Hodological organization of spoken language production and singing in the human brain.

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