Ontology highlight
ABSTRACT:
SUBMITTER: Gromeier M
PROVIDER: S-EPMC103915 | biostudies-literature | 1999 Feb
REPOSITORIES: biostudies-literature
Gromeier M M Bossert B B Arita M M Nomoto A A Wimmer E E
Journal of virology 19990201 2
In the human central nervous system, susceptibility to poliovirus (PV) infection is largely confined to a specific subpopulation of neuronal cells. PV tropism is likely to be determined by cell-external components such as the PV receptor CD155, as well as cell-internal constraints such as the availability of a suitable microenvironment for virus propagation. We reported previously that the exchange of the cognate internal ribosomal entry site (IRES) within the 5' nontranslated region of PV with ...[more]