Dose evaluation of inter- and intra-fraction prostate motion in extremely hypofractionated intensity-modulated proton therapy for prostate cancer.
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ABSTRACT:
SUBMITTER: Feng SQ
PROVIDER: S-EPMC10407426 | biostudies-literature | 2023 Jul
REPOSITORIES: biostudies-literature
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Dose evaluation of inter- and intra-fraction prostate motion in extremely hypofractionated intensity-modulated proton therapy for prostate cancer.
Feng Sen-Quan SQ Brouwer Charlotte L CL Korevaar Erik W EW Vapiwala Neha N Kang-Hsin Wang Ken K Deville Curtiland C Langendijk Johannes A JA Both Stefan S Aluwini Shafak S
Physics and imaging in radiation oncology 20230722
Inter- and intra-fractional prostate motion can deteriorate the dose distribution in extremely hypofractionated intensity-modulated proton therapy. We used verification CTs and prostate motion data calculated from 1024 intra-fractional prostate motion records to develop a voxel-wise based 4-dimensional method, which had a time resolution of 1 s, to assess the dose impact of prostate motion. An example of 100 fractional simulations revealed that motion had minimal impact on planning dose, the acc ...[more]
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