Ontology highlight
ABSTRACT:
SUBMITTER: Bao J
PROVIDER: S-EPMC10413920 | biostudies-literature | 2023 Dec
REPOSITORIES: biostudies-literature
Bao Junhe J Hao Yumeng Y Ni Tingjunhong T Wang Ruina R Liu Jiacun J Chi Xiaochen X Wang Ting T Yu Shichong S Jin Yongsheng Y Yan Lan L Li Xiaomei X Zhang Dazhi D Xie Fei F
Journal of enzyme inhibition and medicinal chemistry 20231201 1
A series of novel triazole derivatives containing aryl-propanamide side chains was designed and synthesised. <i>In vitro</i> antifungal activity studies demonstrated that most of the compounds inhibited the growth of six human pathogenic fungi. In particular, parts of phenyl-propionamide-containing compounds had excellent, broad-spectrum antifungal activity against <i>Candida albicans</i> SC5314, <i>Cryptococcus neoformans</i> 22-21, <i>Candida glabrata</i> 537 and <i>Candida parapsilosis</i> 22 ...[more]