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Cariprazine’s efficacy in treating depressive symptoms – pooled data from schizophrenia, bipolar depression and major depression trials


ABSTRACT:

Introduction

Depressive symptoms are a common feature of schizophrenia (SCH) and define bipolar disorder and major depressive disorder (MDD). Their emergence is related to altered neurotransmission at the serotonin receptors and potentially at dopamine D3 receptors.

Objectives

The aim of this analysis was to examine the efficacy of cariprazine (CAR) in treating depressive symptoms in SCH, bipolar depression (BD) and MDD.

Methods

Clinical trials with randomised, double-blind, placebo

SUBMITTER: McIntyre R 

PROVIDER: S-EPMC10434119 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature

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