Ontology highlight
ABSTRACT:
SUBMITTER: Cano MI
PROVIDER: S-EPMC104618 | biostudies-literature | 1998 Mar
REPOSITORIES: biostudies-literature
Journal of clinical microbiology 19980301 3
Here we present the karyotype analysis and genome sizing of Paracoccidioides brasiliensis, a pathogen refractory to conventional genetic analysis. We have established pulsed-field gel electrophoresis (PFGE) conditions to resolve the high-molecular-weight chromosomal bands of two clinical isolates of P. brasiliensis. Both isolates showed four megabase-sized bands, ranging from 2.0 to 10.0 Mbp. Significant differences in chromosome sizes and in the chromosomal location of genes for the gp43 antige ...[more]