Dataset Information

Effects of anthocyanin supplementation on blood lipid levels: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Dyslipidemia is a major cardiovascular disease risk factor associated with increased mortality. The intake of plant food-derived bioactive compounds is associated with beneficial cardiovascular effects, including decreased blood lipid levels and cardiovascular risk. We aimed to evaluate the effects of anthocyanin intake on blood lipid levels by analyzing relevant randomized controlled trials.

Methods

We searched the PubMed and Embase databases using the "Patient/Population, Intervention, Comparison, and Outcomes" format to determine whether anthocyanin supplementation intervention affected blood lipid levels compared with placebo supplementation in human participants.

Results

A total of 41 studies with 2,788 participants were included in the meta-analysis. Anthocyanin supplementation significantly reduced triglyceride [standardized mean difference (SMD) = -0.10; 95% confidence interval [CI], -0.18, -0.01) and low-density lipoprotein-cholesterol (SMD = -0.16; 95% CI -0.26, -0.07) levels and increased high-density lipoprotein-cholesterol levels (SMD = 0.42; 95% CI 0.20, 0.65).

Discussion

Anthocyanin supplementation significantly improved blood lipid component levels in the included studies. Larger, well-designed clinical trials are needed to further investigate the effects of anthocyanin intake on blood lipid levels and the safety of anthocyanin supplementation for treating dyslipidemia.

Systematic review registration

https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021257087, identifier: CRD42021257087.

SUBMITTER: Jang HH

PROVIDER: S-EPMC10463756 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature

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Publications

Effects of anthocyanin supplementation on blood lipid levels: a systematic review and meta-analysis.

Jang Hwan-Hee HH Hwang In-Guk IG Lee Young-Min YM

Frontiers in nutrition 20230815

<h4>Introduction</h4>Dyslipidemia is a major cardiovascular disease risk factor associated with increased mortality. The intake of plant food-derived bioactive compounds is associated with beneficial cardiovascular effects, including decreased blood lipid levels and cardiovascular risk. We aimed to evaluate the effects of anthocyanin intake on blood lipid levels by analyzing relevant randomized controlled trials.<h4>Methods</h4>We searched the PubMed and Embase databases using the "Patient/Popul ...[more]

PMID: 37649528

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Dataset Information

Effects of anthocyanin supplementation on blood lipid levels: a systematic review and meta-analysis.

Introduction

Methods

Results

Discussion

Systematic review registration

Publications

Effects of anthocyanin supplementation on blood lipid levels: a systematic review and meta-analysis.

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