Ontology highlight
ABSTRACT:
SUBMITTER: Boone BA
PROVIDER: S-EPMC10473691 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
bioRxiv : the preprint server for biology 20231006
DNA methylation mediates silencing of transposable elements and genes in part via recruitment of the Arabidopsis MBD5/6 complex, which contains the methyl-CpG-binding domain (MBD) proteins MBD5 and MBD6, and the J-domain containing protein SILENZIO (SLN). Here we characterize two additional complex members: α-crystalline domain containing proteins ACD15 and ACD21. We show that they are necessary for gene silencing, bridge SLN to the complex, and promote higher order multimerization of MBD5/6 com ...[more]