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Rapid COJEC versus standard induction therapies for high-risk neuroblastoma.


ABSTRACT:

SUBMITTER: Peinemann F 

PROVIDER: S-EPMC10501324 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature

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Rapid COJEC versus standard induction therapies for high-risk neuroblastoma.

Peinemann Frank F   Tushabe Doreen A DA   van Dalen Elvira C EC   Berthold Frank F  

The Cochrane database of systematic reviews 20150519 5


<h4>Background</h4>Neuroblastoma is a rare malignant disease and mainly affects infants and very young children. The tumors mainly develop in the adrenal medullary tissue and an abdominal mass is the most common presentation. The high-risk group is characterized by metastasis and other characteristics that increase the risk for an adverse outcome. In the rapid COJEC induction schedule, higher single doses of selected drugs than standard induction schedules are administered over a substantially s  ...[more]

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