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Predicting apical hypertrophic cardiomyopathy using T-wave inversion: Three case reports.

ABSTRACT:

Background

Apical hypertrophic cardiomyopathy (AHCM) is a subtype of hypertrophic cardiomyopathy. Due to its location, the thickening of the left ventricular apex can be missed on echocardiography. Giant negative T waves (GNTs) in left-sided chest leads are the hallmark electrocardiogram (ECG) change of AHCM.

Case summary

The first patient was a 68-year-old woman complaining of recurrent chest tightness persisting for more than 3 years. The second was a 59-year-old man complaining of spasmodic chest tightness persisting for more than 2 years. The third was a 55-year-old woman complaining of recurrent chest pain persisting for 4 mo. In all three cases, GNTs were observed several years prior to apical cardiac hypertrophy after other causes of T-wave inversion were ruled out.

Conclusion

Electrophysiological abnormalities of AHCM appear earlier than structural abnormalities, confirming the early predictive value of ECG for AHCM.

SUBMITTER: Kang L

PROVIDER: S-EPMC10506034 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature

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Publications

Predicting apical hypertrophic cardiomyopathy using T-wave inversion: Three case reports.

Kang Liang L Li Yi-Hua YH Li Rong R Chu Qing-Min QM

World journal of clinical cases 20230901 25

<h4>Background</h4>Apical hypertrophic cardiomyopathy (AHCM) is a subtype of hypertrophic cardiomyopathy. Due to its location, the thickening of the left ventricular apex can be missed on echocardiography. Giant negative T waves (GNTs) in left-sided chest leads are the hallmark electrocardiogram (ECG) change of AHCM.<h4>Case summary</h4>The first patient was a 68-year-old woman complaining of recurrent chest tightness persisting for more than 3 years. The second was a 59-year-old man complaining ...[more]

PMID: 37727498

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