Ontology highlight
ABSTRACT:
SUBMITTER: van Doorn LJ
PROVIDER: S-EPMC105169 | biostudies-literature | 1998 Sep
REPOSITORIES: biostudies-literature
van Doorn L J LJ Figueiredo C C Sanna R R Pena S S Midolo P P Ng E K EK Atherton J C JC Blaser M J MJ Quint W G WG
Journal of clinical microbiology 19980901 9
The diversity of the gene encoding the vacuolating cytotoxin (vacA) of Helicobacter pylori was analyzed in 98 isolates obtained from different geographic locations. The studies focused on variation in the previously defined s and m regions of vacA, as determined by PCR and direct sequencing. Phylogenetic analysis revealed the existence of four distinct types of s-region alleles: aside from the previously described s1a, s1b, and s2 allelic types, a novel subtype, designated s1c, was found. Subtyp ...[more]