Ontology highlight
ABSTRACT:
SUBMITTER: Habazaki M
PROVIDER: S-EPMC10517024 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
Habazaki Misuzu M Mizumoto Shinsuke S Kajino Hidetoshi H Kujirai Tomoya T Kurumizaka Hitoshi H Kawashima Shigehiro A SA Yamatsugu Kenzo K Kanai Motomu M
Nature communications 20230922 1
Life emerges from a network of biomolecules and chemical reactions catalyzed by enzymes. As enzyme abnormalities are often connected to various diseases, a chemical catalyst promoting physiologically important intracellular reactions in place of malfunctional endogenous enzymes would have great utility in understanding and treating diseases. However, research into such small-molecule chemical enzyme surrogates remains limited, due to difficulties in developing a reactive catalyst capable of acti ...[more]