Ontology highlight
ABSTRACT:
SUBMITTER: Belluti S
PROVIDER: S-EPMC10526871 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
Belluti Silvia S Imbriano Carol C Casarini Livio L
Cancers 20230920 18
Estrogens are almost ubiquitous steroid hormones that are essential for development, metabolism, and reproduction. They exert both genomic and non-genomic action through two nuclear receptors (ERα and ERβ), which are transcription factors with disregulated functions and/or expression in pathological processes. In the 1990s, the discovery of an additional membrane estrogen G-protein-coupled receptor augmented the complexity of this picture. Increasing evidence elucidating the specific molecular m ...[more]