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The Chemical Inhibitors of Endocytosis: From Mechanisms to Potential Clinical Applications.


ABSTRACT: Endocytosis is one of the major ways cells communicate with their environment. This process is frequently hijacked by pathogens. Endocytosis also participates in the oncogenic transformation. Here, we review the approaches to inhibit endocytosis, discuss chemical inhibitors of this process, and discuss potential clinical applications of the endocytosis inhibitors.

SUBMITTER: Szewczyk-Roszczenko OK 

PROVIDER: S-EPMC10527932 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature

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The Chemical Inhibitors of Endocytosis: From Mechanisms to Potential Clinical Applications.

Szewczyk-Roszczenko Olga Klaudia OK   Roszczenko Piotr P   Shmakova Anna A   Finiuk Nataliya N   Holota Serhii S   Lesyk Roman R   Bielawska Anna A   Vassetzky Yegor Y   Bielawski Krzysztof K  

Cells 20230919 18


Endocytosis is one of the major ways cells communicate with their environment. This process is frequently hijacked by pathogens. Endocytosis also participates in the oncogenic transformation. Here, we review the approaches to inhibit endocytosis, discuss chemical inhibitors of this process, and discuss potential clinical applications of the endocytosis inhibitors. ...[more]

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