Ontology highlight
ABSTRACT:
SUBMITTER: Zeckanovic A
PROVIDER: S-EPMC10528122 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
Zeckanovic Aida A Fuchs Philipp P Heesen Philip P Bodmer Nicole N Otth Maria M Scheinemann Katrin K
Current oncology (Toronto, Ont.) 20230920 9
Adolescents and young adults (AYA) with acute lymphoblastic leukemia (ALL) have significantly worse outcomes than their younger counterparts. Current treatment guidelines rely mostly on non-randomized retrospective studies. We performed a systematic review of studies published within the last 15 years comparing pediatric-inspired regimens (PIR) versus adult-type regimens or performing an age-stratified analysis of outcomes in the AYA population. Due to the heterogeneity of data, a meta-analysis ...[more]