Modulation of Skin Cancer by the Stimulator of Interferon Genes.
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ABSTRACT:
SUBMITTER: Oscherwitz M
PROVIDER: S-EPMC10530941 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
Publications
Modulation of Skin Cancer by the Stimulator of Interferon Genes.
Oscherwitz Max M Jiminez Victoria V Terhaar Hanna H Yusuf Nabiha N
Genes 20230913 9
Morbidity and mortality from skin cancer continue to rise domestically and globally, and melanoma and non-melanoma skin cancers are a topic of interest in the dermatology and oncology communities. In this review, we summarize the stimulator of interferon genes (STING) pathway, its specific role in the pathogenesis of DNA damage and skin cancer, and STING-specific therapies that may fight both melanoma and non-melanoma skin (NMSC) cancers. Furthermore, we discuss specific portions of the STING pa ...[more]
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