Ontology highlight
ABSTRACT:
SUBMITTER: Schuck P
PROVIDER: S-EPMC10542142 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature
bioRxiv : the preprint server for biology 20230801
Molecular mimicry of short linear interaction motifs has emerged as a key mechanism for viral proteins binding host domains and hijacking host cell processes. Here, we examine the role of RNA-virus sequence diversity in the dynamics of the virus-host interface, by analyzing the uniquely vast sequence record of viable SARS-CoV-2 species with focus on the multi-functional nucleocapsid protein. We observe the abundant presentation of motifs encoding several essential host protein interactions, alon ...[more]