Ontology highlight
ABSTRACT:
SUBMITTER: Soltysova A
PROVIDER: S-EPMC10547624 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Soltysova Andrea A Begerova Patricia P Jakic Kristina K Kozics Katarina K Sramkova Monika M Meese Eckart E Smolkova Bozena B Gabelova Alena A
Cell biology and toxicology 20220101 5
The unique physicochemical properties make inorganic nanoparticles (INPs) an exciting tool in diagnosis and disease management. However, as INPs are relatively difficult to fully degrade and excrete, their unintended accumulation in the tissue might result in adverse health effects. Herein, we provide a methylome-transcriptome framework for chronic effects of INPs, commonly used in biomedical applications, in human kidney TH-1 cells. Renal clearance is one of the most important routes of nanopar ...[more]